First 12-Week Plan for a New R&D Lab Manager

Congratulations! Now, you are a manager of R&D lab. Either you call it the first 100-day or the first 3-month, it is critical for you to plant a solid footing, establish credibility,  and demonstrate leadership. Here, I present you a 12-week plan to build a foundation for future success. Week 1: Group Get to know …

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in vitro Skin Tissue Model in Topical Product Development

Introduction Topical diseases are becoming increasingly attractive to the pharmaceutical industry as an expanding and profitable sector. Once considered a niche therapeutic segment, today skin diseases collectively outnumber conditions such as obesity, hypertension and cancer. The global market for skin therapy reached $17.1 billion in 2015 and with a five-year compound annual growth rate (CAGR) …

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Resources for Topical Generic Product Development

With many blockbuster brand drugs at or near the edge of the so called “patent cliff”, and with significant technical hurdles in biosimilar development, some generic companies are shifting their attention to additional dosage forms or niche products to create product portfolio diversity. One of the market segments that offers multiple sub-billion-dollar product opportunities is …

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No Yield to Yield Stress

Semi-solid and liquid drug products display complex rheological behaviors, which have significant impact on patient compliance, product manufacturability and stability. Aside from Ketchup or toothpaste, there are ample examples of semi-solid and liquid dosage forms where the rheology plays a delicate role in product characteristics. For instance, a medicated shampoo should be easily poured out …

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